A new type of biocompatible fluorescent probe AFN for fixed and live cell imaging of intracellular lipid droplets.

نویسندگان

  • Ashutosh Sharma
  • Shahida Umar
  • Parmita Kar
  • Kavita Singh
  • Monika Sachdev
  • Atul Goel
چکیده

We discovered a new class of nontoxic, highly fluorogenic and biocompatible probe AFN for selective staining of intracellular Lipid Droplets (LDs) in both fixed and live human cervical cancer cells (HeLa) and 3T3-L1 pre-adipocytes without any background artifacts. The salient features of the probe are its visible excitation maximum, aqueous compatibility, selectivity and remarkable stability (for more than a week) in live cells, even better than commercially available Nile red.

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عنوان ژورنال:
  • The Analyst

دوره 141 1  شماره 

صفحات  -

تاریخ انتشار 2016